Genome Engineering
- Humab can utilize genome engineering technologies effectively by overcoming the limits of restriction enzymes.
- Genome engineering can be applied to solving many of the challenges facing the humankind such as health issues, food shortages, and environmental pollution.
- Humab is capable of undertaking large-scale and extensive genome engineering tasks on a chromosome level by utilizing a diverse array of programmable nucleases (crispr, talen, zfn, etc.) and microcell-mediated chromosome transfer (MMCT) technologies.
- Such technological advantages of Humab over other genetic engineering companies expand the application of genome engineering to another level.
- Antibodies in mammals are formed through the biosynthesis of genes from three separate chromosomes: heavy chains and the kappa and lambda light chains.
- Humab's transgenic antibody platform (SynTheseTM) is engineered so that the three massive genomic sequences in mouse chromosomes are replaced with human genes.
- The resultant SynTheseTM produces fully-human antibodies that fight against disease-causing antigens.
- Humab is opening the door to a new era of genome engineering by applying our proprietary technology to not only immunoglobulin genes but also other diverse and large-scale genes whose sheer size has so far been difficult to handle.
- We intend to open the door to a brighter future for the humankind by providing diverse and innovative solutions and products as following.
